Invitrogen™ PPP6C Polyclonal Antibody

Sheep Polyclonal Antibody

Supplier:  Invitrogen™ PA112400

Catalog No. 01-674-133

Description

PPP6C Polyclonal Antibody for Western Blot, IP

Distinct DNA repair pathways minimize the consequences of mutagenic events. Reactive oxygen species (ROS) are highly reactive atoms with an unpaired electron that are conducive to double-strand DNA breaking events. Artemis, named after the Greek goddess for the protection of children, is one of the major proteins contributing to the preservation of double-strand breaks in DNA by cutting away the damaged parts of the DNA, which allows the strands to rejoin. Artemis is a single-strand-specific 5' to 3' exonuclease that forms a complex with the 469 kDa DNA-dependent protein kinase (DNA-PKcs). DNA-PKcs phosphorylates Artemis, and Artemis acquires endonucleolytic activity on 5' and 3' overhangs and hairpins. These activities are essential for V(D)J recombination and for the 5' and 3' overhang processing in nonhomologous DNA end joining.

Specifications

• Antigen: PPP6C
• Classification: Polyclonal
• Formulation: PBS with 0.08% sodium azide
• Gene Accession No.: O00743, Q64620, Q9CQR6
• Gene Symbols: Ppp6c
• Immunogen: Synthetic peptide.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Bovine
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Gene: Ppp6c
• Gene Alias: 2310003C10Rik; ANKRD33; FLJ34236; PP6; PP6C; PPP6; PPP6C; Ppv; PP-V; protein phosphatase 6 catalytic subunit; protein phosphatase 6, catalytic subunit; protein phosphatase V; serine/threonine protein phosphatase catalytic subunit; serine/threonine-protein phosphatase 6 catalytic subunit; Serine/threonine-protein phosphatase 6 catalytic subunit, N-terminally processed; UNQ5837
• Host Species: Sheep
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 171121, 511058, 5537, 67857
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov