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Invitrogen™ PR3 Monoclonal Antibody (PR3G-2), FITC
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA549093
Description
The monoclonal antibody PR3G-2 was produced by immunization of mice with a crude granule extract.
Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369). May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279). [UniProt].
Specifications
PR3 | |
Monoclonal | |
100 μg/mL | |
PBS with 1% BSA and 0.02% sodium azide | |
P24158 | |
PRTN3 | |
Monoclonal antibody PR3G-2 reacts with human proteinase 3 (PR3), a 30 kDa protein. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
Flow Cytometry, Functional Assay, Inhibition Assays, Western Blot | |
PR3G-2 | |
FITC | |
PRTN3 | |
ACPA; AGP7; azurophil granule protein 7; CANCA; C-ANCA; C-ANCA antigen; leukocyte proteinase 3; MBN; MBT; mPR3; Myeloblastin; neutrophil proteinase 4; NP4; NP-4; P29; PR3; PR-3; Proteinase 3; PRTN3; serine proteinase, neutrophil; wegener autoantigen; Wegener granulomatosis autoantigen | |
Mouse | |
Protein G | |
RUO | |
5657 | |
4°C, store in dark | |
Liquid |
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