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Invitrogen™ PR3 Monoclonal Antibody (PR3G-2), FITC
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Catalog No. FERMA549093
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100 μg
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Catalog No. Quantity
FERMA549093 100 μg
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Catalog No. FERMA549093 Supplier Invitrogen™ Supplier No. MA549093
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Description

Mouse Monoclonal Antibody

The monoclonal antibody PR3G-2 was produced by immunization of mice with a crude granule extract.

Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369). May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen PR3
Applications Flow Cytometry, Functional Assay, Inhibition Assays, Western Blot
Classification Monoclonal
Clone PR3G-2
Concentration 100 μg/mL
Conjugate FITC
Formulation PBS with 1% BSA and 0.02% sodium azide
Gene PRTN3
Gene Accession No. P24158
Gene Alias ACPA; AGP7; azurophil granule protein 7; CANCA; C-ANCA; C-ANCA antigen; leukocyte proteinase 3; MBN; MBT; mPR3; Myeloblastin; neutrophil proteinase 4; NP4; NP-4; P29; PR3; PR-3; Proteinase 3; PRTN3; serine proteinase, neutrophil; wegener autoantigen; Wegener granulomatosis autoantigen
Gene Symbols PRTN3
Host Species Mouse
Immunogen Monoclonal antibody PR3G-2 reacts with human proteinase 3 (PR3), a 30 kDa protein.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5657
Target Species Human
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG1
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