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Invitrogen™ PR3 Polyclonal Antibody
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Catalog No. PIPA585928 Shop All Thermo Scientific Products
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PIPA585928 100 μL
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Catalog No. PIPA585928 Supplier Invitrogen™ Supplier No. PA585928
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Description

Rabbit Polyclonal Antibody

PR3 Polyclonal Antibody for IHC (P), Western Blot

Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369). May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen PR3
Applications Immunohistochemistry (Paraffin), Western Blot, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA, 50% Glycerol and 0.05% sodium azide; pH 7.4
Gene PRTN3
Gene Accession No. P24158, Q61096
Gene Alias ACPA; AGP7; azurophil granule protein 7; CANCA; C-ANCA; C-ANCA antigen; leukocyte proteinase 3; MBN; MBT; mPR3; Myeloblastin; neutrophil proteinase 4; NP4; NP-4; P29; PR3; PR-3; Proteinase 3; PRTN3; serine proteinase, neutrophil; wegener autoantigen; Wegener granulomatosis autoantigen
Gene Symbols PRTN3
Host Species Rabbit
Immunogen Recombinant protein within Human PRTN3 aa 50-248.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19152, 5657
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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