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PRAS40 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501733255 Shop All Proteintech Group Inc Products
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50-173-3255 150 μL
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Catalog No. 50-173-3255 Supplier Proteintech Group Inc Supplier No. 210971AP150UL
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Description

Rabbit Polyclonal Antibody

The Akt signaling pathway contributes to the regulation of apoptosis after a variety of cell death signals. AKT1S1, also known as PRAS40, is a proline-rich substrate of the kinase AKT1 and is thought to play a role in neuroprotection mediated by nerve growth factor (NGF) after transient focal cerebral ischemia. AKT1S1 is also a substrate and potential regulator of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Treatment with the insulin-like growth factor-1 (IGF1) can indusce the phosphorylation of AKT1S1 via the PI3K/AKT signaling pathway in PC12 cells.

Specifications

Antigen PRAS40
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.81 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene AKT1S1
Gene Accession No. Q96B36
Gene Alias AKT1S1, AKTS1, Lobe, PRAS40, Proline rich AKT1 substrate 1
Gene Symbols AKT1S1
Host Species Rabbit
Immunogen PRAS40 Fusion Protein Ag15355
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84335
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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