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Invitrogen™ PRDM12 Polyclonal Antibody
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Catalog No. PIPA5110215
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PIPA5110215 100 μL
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Catalog No. PIPA5110215 Supplier Invitrogen™ Supplier No. PA5110215
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LGIFSKTWIK AGTEMGPFTG RVIAPEHVDI CKNNNLMWEV FNEDGTVRYF IDASQEDHRS WMTYIKCARN EQEQNLEVVQ IGTSIFYKAI EMIPPDQELL VWYGNSHNTF LGIPGVPGLE EDQKKNKHED FHPADSAAGP AGRMRCVICH RGFNSRSNLR SHMRIHTLDK PFVCRFCNRR FSQSSTLRNH VRLHTGERPY KCQVCQSAYS QLAGLRAHQK SARHRPPSTA L.

This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception. The encoded protein contains an N-terminal PRDI-BF1 and RIZ homology (PR) domain, a SET domain, and three C-terminal C2H2 zinc finger DNA-binding domains. Naturally occurring mutations in this gene are associated with congenital insensitivity to pain (CIP), and hereditary sensory and autonomic neuropathies (HSAN's) affecting peripheral sensory and autonomic neurons. Deregulation of this gene is associated with solid cancers and hematological malignancies including chronic myeloid leukemia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRDM12
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.95 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene PRDM12
Gene Accession No. A2AJ77, Q9H4Q4
Gene Alias Gm998; HSAN8; PFM9; PR domain 12; PR domain containing 12; PR domain zinc finger protein 12; PR domain-containing protein 12; PRDM12; PR-domain containing protein 12; PR-domain zinc finger protein 12; RP11-57C19.7
Gene Symbols PRDM12
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 381359, 59335
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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