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Invitrogen™ PRDX3 Monoclonal Antibody (6E6E12)
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Catalog No. FEMA550291
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100 μL
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FEMA550291 100 μL
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Catalog No. FEMA550291 Supplier Invitrogen™ Supplier No. MA550291
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Description

Mouse Monoclonal Antibody

PRDX3 Monoclonal Antibody for Western Blot, ICC/IF, Flow, ELISA

Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20-30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRDX3
Applications ELISA, Flow Cytometry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 6E6E12
Concentration 0.85 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300, 0.1% sodium azide; pH 7.3
Gene PRDX3
Gene Accession No. P30048
Gene Alias antioxidant protein; antioxidant protein 1; anti-oxidant protein 1; Aop1; AOP-1; AW822249; D0Tohi1; Ef2l; HBC189; Mer5; mitochondrial thioredoxin dependent peroxide reductase; mitochondrial Trx dependent peroxide reductase; perioredoxin-3; peroxiredoxin 3; peroxiredoxin III; Peroxiredoxin-3; Prdx3; PRO1748; Protein MER5; Protein MER5 homolog; Prx; Prx 3; PRx III; Prx3; PRX-3; Prx-III; SP22; SP-22; TDXM; thioredoxin-dependent peroxide reductase, mitochondrial
Gene Symbols PRDX3
Host Species Mouse
Immunogen Recombinant Human Thioredoxin-dependent peroxide reductase, mitochondrial protein (63-256AA).
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10935
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG1
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