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Invitrogen™ PRG2 Polyclonal Antibody
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Catalog No. PIPA5102628
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PIPA5102628 100 μL
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Catalog No. PIPA5102628 Supplier Invitrogen™ Supplier No. PA5102628
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total PRG2.

The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRG2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene PRG2
Gene Accession No. P13727, Q61878
Gene Alias BMPG; bone marrow proteoglycan; bone-marrow proteoglycan; EMBP; Eosinophil granule major basic protein; eosinophil major basic protein; LPR3; major basic protein 1; MBP; MBP1; Mbp-1; mMBP; mMBP-1; natural killer cell activator; Pregnancy-associated major basic protein; PRG2; PRG-2; proMBP; Proteoglycan 2; proteoglycan 2 preproprotein; proteoglycan 2, bone marrow; proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein); proteoglycan 2, pro eosinophil major basic protein
Gene Symbols PRG2
Host Species Rabbit
Immunogen A synthesized peptide derived from human PRG2(Accession P13727), corresponding to amino acid residues P42-E92.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19074, 5553
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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