Invitrogen™ PRG2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102628

Catalog No. PIPA5102628

Description

Antibody detects endogenous levels of total PRG2.

The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases.

Specifications

• Antigen: PRG2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PRG2
• Gene Alias: BMPG; bone marrow proteoglycan; bone-marrow proteoglycan; EMBP; Eosinophil granule major basic protein; eosinophil major basic protein; LPR3; major basic protein 1; MBP; MBP1; Mbp-1; mMBP; mMBP-1; natural killer cell activator; Pregnancy-associated major basic protein; PRG2; PRG-2; proMBP; Proteoglycan 2; proteoglycan 2 preproprotein; proteoglycan 2, bone marrow; proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein); proteoglycan 2, pro eosinophil major basic protein
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19074, 5553
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P13727, Q61878
• Gene Symbols: PRG2
• Immunogen: A synthesized peptide derived from human PRG2(Accession P13727), corresponding to amino acid residues P42-E92.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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