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Abcam PRIMA-1MET, P53 Activity, >98% Purity, Solid, 10 mg

Catalog No. 502704987
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50-270-4987 10 mg
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Catalog No. 50-270-4987 Supplier Abcam Supplier No. AB14597410MG
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Description

Methylated derivative of PRIMA-1 that restores wild-type p53 function and triggers apoptosis in tumor cells.

  • Molecular Weight: 199.25 Da
  • Purity: >98%
  • Form: Solid
  • CAS Number: 5291-32-7
  • Key Features: Methylated derivative of PRIMA-1 (ab141641); restores wild-type conformation and function to mutant p53; triggers apoptosis in tumor cells; acts synergistically with chemotherapeutic agents; inhibits thioredoxin reductase 1 (TrxR1).
  • Storage: Store at +4°C.
  • Shipping: Ambient - Can Ship with Ice.
  • Composition: 100% 2-(hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one.

The product is subject to the following: Abcam Restricted Use Statement

Specifications

Content And Storage Store at 4°C.
Shipping Condition Ambient
Substrate Properties Chemical Substrate
Target Molecule p53, Thioredoxin Reductase 1
Alternate Part Number APR-246
Buffer 100% 2-(hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one
Form Solid
Formulation 100% 2-(hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one
Quantity 10 mg
For Use With (Application) p53 activity, apoptosis induction, tumor cell proliferation inhibition, thioredoxin reductase 1 inhibition
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