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Abcam PRIMA-1MET, p53 Activity, >98% Purity, Solid, 25 mg

Catalog No. 502704986
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50-270-4986 25 mg
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Catalog No. 50-270-4986 Supplier Abcam Supplier No. AB14597425MG
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Description

Methylated derivative of PRIMA-1 that restores mutant p53 function and induces apoptosis in tumor cells.

  • Molecular weight: 199.25 Da
  • Purity: >98%
  • Physical form: Solid
  • Function: Methylated derivative of PRIMA-1 that restores wild-type conformation and function to mutant p53 and triggers apoptosis in tumor cells
  • Mechanism of action: Inhibits thioredoxin reductase 1 (TrxR1)
  • Applications: Inhibits tumor cell proliferation and acts synergistically with chemotherapeutic agents
  • Storage: Store at +4°C

The product is subject to the following: Abcam Restricted Use Statement

Specifications

Target Molecule p53, Thioredoxin Reductase 1
Shipping Condition Ambient
Form Solid
Alternate Part Number APR-246
Buffer 100% 2-(hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one
Content And Storage Store at 4°C.
Formulation 100% 2-(hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one
Quantity 25 mg
For Use With (Application) p53 activity, apoptosis induction, tumor cell proliferation inhibition, thioredoxin reductase 1 inhibition
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