PRKAB2 Mouse anti-Human, Clone: OTI4H4, liquid, TrueMAB™

Catalog No.	Quantity
50-168-2059	100 μL

Catalog No. 50-168-2059 Supplier OriGene Supplier No. TA808333

Description

Mouse Monoclonal Antibody

AMPK Beta 2 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.

Specifications

• Antigen: PRKAB2
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI4H4
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: PRKAB2
• Gene Accession No.: O43741
• Gene Alias: protein kinase AMP-activated non-catalytic subunit beta 2
• Gene Symbols: PRKAB2
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human PRKAB2 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5565
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1