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Invitrogen™ PRL1 Polyclonal Antibody
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Catalog No. PIPA567528
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PIPA567528 100 μL
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Catalog No. PIPA567528 Supplier Invitrogen™ Supplier No. PA567528
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Description

Rabbit Polyclonal Antibody

Predicted to react with Mouse and Rat samples.

The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells. PRL phosphatases increase cell proliferation by stimulating progression from G1 into S phase. PRL-1 function is regulated in a cell cycle-dependent manner and implicate PRL-1 in regulating progression through mitosis, possibly by modulating spindle dynamics.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRL1
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene PTP4A1
Gene Accession No. Q63739, Q78EG7, Q93096
Gene Alias AA415290; AU019864; C130021B01; DKFZp779M0721; HH72; PRL1; Prl-1; protein tyrosine phosphatase 4a1; protein tyrosine phosphatase type IVA 1; protein tyrosine phosphatase type IVA protein 1; protein tyrosine phosphatase type IVA, member 1; protein-tyrosine phosphatase 4a1; Protein-tyrosine phosphatase of regenerating liver 1; PTP(CAAX1); PTP(CAAXI); PTP4A1; PTP4A1 protein; PTP4A2; PTPCAAX1; RP5-1148A21.2
Gene Symbols PTP4A1
Host Species Rabbit
Immunogen Fusion protein of human PRL1.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19243, 29463, 7803
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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