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Invitrogen™ PRMT1 Monoclonal Antibody (GT779)
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Catalog No. PIMA527756
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100 μL
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Catalog No. Quantity
PIMA527756 100 μL
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Catalog No. PIMA527756 Supplier Invitrogen™ Supplier No. MA527756
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Description

Mouse Monoclonal Antibody

Positive Control: Neuro2A, GL261, NIH-3T3, Raw264.7, C2C12, 293T, A431, HeLa, HepG2 Predicted Reactivity: Rat (100%), Xenopus laevis (100%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

PRMT1 is a member of the protein arginine N-methyltransferase (PRMT) family. Arginine methylation is an irreversible post translational modification which has been implicated in RNA processing and trafficking, receptor-mediated signaling, and transcription. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These proteins include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Increased expression of PRMT1 may play a role in various types of cancer.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRMT1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone GT779
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene PRMT1
Gene Accession No. Q63009, Q99873, Q9JIF0
Gene Alias 6720434D09Rik; ANM1; arginine N-methyltransferase 1; AW214366; HCP1; heterogeneous nuclear ribonucleoprotein methyltransferase 1-like 2; heterogeneous nuclear ribonucleoproteins methyltransferase-like 2; histone-arginine N-methyltransferase PRMT1; HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 2; HMT1 hnRNP methyltransferase-like 2; HMT1 hnRNP methyltransferase-like 2 isoform 3; HMT2; Hrmt1l2; interferon receptor 1-bound protein 4; IR1B4; Mrmt1; PRMT1; protein arginine methyltransferase 1; protein arginine N-methyltransferase 1
Gene Symbols PRMT1
Host Species Mouse
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PRMT1. The exact sequence is proprietary.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15469, 3276, 60421
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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