PRMT1 Mouse anti-Human, Mouse, Clone: GT779, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527756
Positive Control: Neuro2A, GL261, NIH-3T3, Raw264.7, C2C12, 293T, A431, HeLa, HepG2 Predicted Reactivity: Rat (100%), Xenopus laevis (100%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.PRMT1 is a member of the protein arginine N-methyltransferase (PRMT) family. Arginine methylation is an irreversible post translational modification which has been implicated in RNA processing and trafficking, receptor-mediated signaling, and transcription. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These proteins include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Increased expression of PRMT1 may play a role in various types of cancer.
|PBS with no preservative|
|ANM1, protein arginine methyltransferase 1, IR1B4, HRMT1L2, HCP1|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PRMT1. The exact sequence is proprietary.|
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