Invitrogen™ PRMT4 Monoclonal Antibody (3H2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA515796

Catalog No. PIMA515796

Description

MA5-15796 targets CARM1 in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human, Non-human primate, Mouse and Rat samples. The MA5-15796 immunogen is purified recombinant fragment of human CARM1 expressed in E. Coli. MA5-15796 detects CARM1 which has a predicted molecular weight of approximately 65kDa.

Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in DNA packaging, transcription regulation, signal transduction, mRNA stability, metabolism of nascent pre-RNA, and transcriptional activation. Tissue specificity: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia.

Specifications

• Antigen: PRMT4
• Classification: Monoclonal
• Concentration: Conc. not determined
• Formulation: ascites with 0.03% sodium azide
• Gene Accession No.: Q4AE70, Q86X55, Q9WVG6
• Gene Symbols: Carm1
• Immunogen: Purified recombinant fragment of human CARM1 expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 10498, 363026, 59035
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ChIP Assay, ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 3H2
• Conjugate: Unconjugated
• Gene: Carm1
• Gene Alias: Carm1; coactivator associated arginine methyltransferase 1; coactivator-associated arginine methyltransferase 1; coactivator-associated arginine methyltransferase 1 variant 5; histone-arginine methyltransferase CARM1; PRMT4; protein arginine methyltransferase; protein arginine N-methyltransferase 4
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Monkey
• Product Type: Antibody
• Isotype: IgG1