PRMT5 Monoclonal Antibody (OTI3E6), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA807620

Catalog No. 50-168-1653

Description

Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.

Specifications

• Antigen: PRMT5
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O14744
• Gene Symbols: PRMT5
• Immunogen: Human recombit protein fragment corresponding to amino acids 238-499 of human PRMT5 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI3E6
• Conjugate: Unconjugated
• Gene: PRMT5
• Gene Alias: HRMT1L5, IBP72, JBP1, SKB1, SKB1Hs
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10419
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid