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PRMT6 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501558816
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50-155-8816 20 μL
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Catalog No. 50-155-8816 Supplier Bethyl Laboratories, Inc Supplier No. A300929AT
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predicted to

Protein arginine N-methyltransferase 6 (PRMT6) PRMT6 demonstrates type I PRMT activity, capable of forming both omega-N monomethylarginine and asymmetric dimethylarginine derivatives on the recombit glycine- and arginine-rich substrates. cts as a transcriptional coactivator of a number of steroid hormone receptors including ESR1, ESR2, PGR and NR3C1. Promotes fasting-induced transcriptional activation of the gluconeogenic program through methylation of the CRTC2 transcription coactivator. May play a role in innate immunity against HIV-1 in case of infection by methylating and impairing the function of various HIV-1 proteins such as Tat, Rev and Nucleocapsid protein p7.

Specifications

Antigen PRMT6
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene PRMT6
Gene Accession No. Q96LA8
Gene Alias FLJ10559, FLJ51477, HRMT1L6
Gene Symbols PRMT6
Host Species Rabbit
Immunogen Between 325 and C-term
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55170
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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