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Invitrogen™ pro-Brain Natriuretic Peptide Monoclonal Antibody (24E11)
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Catalog No. MA120631
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200 μg
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Catalog No. Quantity
MA120631 200 μg
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Catalog No. MA120631 Supplier Invitrogen™ Supplier No. MA120631
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Description

Mouse Monoclonal Antibody

MA1-20631 detects proBNP in human samples.

In cardiac tissue brain natriuretic peptide (BNP) is synthesized as 134 amino acid precursor (prepro-BNP), which is cleaved by proteases to form a 26 aa 'signal' peptide and a 108 aa pro-BNP. Proteolytic digestion of pro-BNP results in formation of 76 aa amino-terminal NT-proBNP and biologically active 32 aa BNP hormone molecule. Both proBNP and NTproBNP circulate in human plasma and have been proposed as markers for early diagnosis of left ventricular dysfunction as well as prognostic markers of possible cardiac complications at patients with heart failure.
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Specifications

Antigen pro-Brain Natriuretic Peptide
Applications ELISA, Western Blot
Classification Monoclonal
Clone 24E11
Concentration 5.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene NPPB
Gene Accession No. P16860
Gene Alias 5 kDa cardiac natriuretic peptide; AA408272; BNF; BNP; BNP(1-28); BNP(1-29); BNP(1-30); BNP(1-32); BNP(2-31); BNP(3-29); BNP(3-30); BNP(3-32); BNP(4-27); BNP(4-29); BNP(4-30); BNP(4-31); BNP(4-32); BNP(5-29); BNP(5-31); BNP(5-32); BNP32; BNP-34; Brain natriuretic factor; brain natriuretic peptide; Brain natriuretic peptide 32; Brain natriuretic peptide 45; brain type natriuretic peptide; gamma-brain natriuretic peptide; Iso-ANP; natriuretic peptide B; natriuretic peptide precursor B; natriuretic peptide precursor type B; natriuretic peptide type B; natriuretic peptides B; natriuretic protein; Nppb; NTproBNP; pro-BNP; type-B natriuretic factor
Gene Symbols NPPB
Host Species Mouse
Immunogen Synthetic N-terminal pro brain natriuretic peptide (NT-proBNP), corresponding to amino acid residues a.a. 61-76. The peptides used for immunization were conjugated with carrier protein.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4879
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG2a
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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