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AdipoGen Progranulin (human) (rec.) (untagged),Protein
SDP

Supplier:  AdipoGen AG40A0188YC050

Encompass_Preferred

Progranulin (human) (rec.) (untagged), AdipoGen Life Sciences. Protein. Signal peptide and human progranulin (aa 1-593) is untagged. Reflects the native sequence with no additional aa. Source: HEK 293 cells. Endotoxin content: <0.01EU/¿g purified protein (LAL test; Lonza). Lyophilized. Contains PBS. Purity: >98% (SDS-PAGE). Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. Progranulin is a biomarker for FTLD, other types of Alzheimer¿s Disease (AD) and potentially for MCI (Mild Cognitive Impairment).

Catalog No. 50-463-983


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