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CPC Scientific H-Thr-D-Ala-Leu-Ile-Asp-Asn-Asn-Ala-Thr-Glu-Glu-Ile-Leu-Tyr-OH (trifluoroacetate salt) 5MG
Supplier: CPC Scientific PROS001B
This 14-mer prosaptide sequence is derived from the active neurotrophic region in the amino-terminal portion of the saposin C domain. Synthetic peptides derived from this region are biologically active and are named ?prosaptides.? Prosaposin and prosaptides are active on a variety of neuronal cells, stimulating sulfatide synthesis and increasing sulfatide concentration in Schwann cells and oligodendrocytes. This indicates that prosaposin and prosaptides are trophic factors for myelin formation.ONE-LETTER SEQUENCE: TaLIDNNATEEILYMOLECULAR FORMULA: C69H110N16O26MOLECULAR WEIGHT:1579.70STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [196391-82-9], RESEARCH AREA: NeuropeptidesREFERENCES: Campana, M. et al. FASEB J. 12, 307 (1998); Hiraiwa, M. et al. Proc. Natl. Acad. Sci. USA 94, 4778 (1997); Taylor, E. et al. Pharmacol. 295, 190 (2000); Calcutt, NA. et al. Anesthesiology 93, 1271 (2000).
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