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Abcam Prostratin, PKC Activator, Solid, 1 mg

Catalog No. 502707177
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50-270-7177 1 mg
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Catalog No. 50-270-7177 Supplier Abcam Supplier No. AB1208801MG
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Description

Potent PKC activator that reactivates HIV-1 latency via NF-κB activation and downregulates CD4, CXCR4, and CCR5 expression.

  • Molecular Weight: 390.48 g/mol
  • Biological Activity: PKC activator; reactivates HIV-1 latency (IC50 = ~0.5 μM) via PKC-dependent NF-κB activation
  • Mechanism: Downregulates expression of HIV-1 receptor CD4 and its co-receptors CXCR4 and CCR5 in vitro
  • Characteristics: Non-tumor promoting
  • Form: Solid

The product is subject to the following: Abcam Restricted Use Statement

Specifications

Content And Storage Store at -20°C.
Form Solid
Target Molecule Protein Kinase C
Shipping Condition Blue Ice
Formulation 100% Prostratin
Quantity 1 mg
For Use With (Application) PKC activation, HIV-1 latency reactivation
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