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Abcam Prostratin, PKC Activator, Solid, 500 μg

Catalog No. 502707176
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50-270-7176 500 μg
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Catalog No. 50-270-7176 Supplier Abcam Supplier No. AB120880500UG
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Description

Potent PKC activator that reactivates HIV-1 latency and downregulates CD4, CXCR4, and CCR5 expression.

  • Molecular weight: 390.48 g/mol
  • Biological activity: PKC activator; reactivates HIV-1 latency (IC50 = ~0.5 μM) via PKC-dependent NF-κB activation
  • In vitro effects: Downregulates HIV-1 receptor CD4 and co-receptors CXCR4 and CCR5
  • Characteristics: Non-tumor promoting
  • Physical form: Solid
  • Purity: 100% Prostratin

The product is subject to the following: Abcam Restricted Use Statement

Specifications

Shipping Condition Blue Ice
Format Vial
Content And Storage Store at -20°C.
Form Solid
Substrate Properties Chemical Substrate
Target Molecule Protein Kinase C
Quantity 500 μg
For Use With (Application) PKC activation, HIV-1 latency reactivation
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