Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Invitrogen™ Protein APC Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA530580
Description
Recommended positive controls: 293T, A431, HeLa, HepG2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
Specifications
Protein APC | |
Polyclonal | |
Unconjugated | |
Apc | |
adenomatosis polyposis coli; adenomatosis polyposis coli tumor suppressor; adenomatous polyposis coli; adenomatous polyposis coli protein; AI047805; APC; APC, WNT signaling pathway regulator; AU020952; AW124434; BTPS2; CC1; Deleted in polyposis 2.5; DP2; DP2.5; DP3; FAP; FPC; GS; mAPC; Min; multiple intestinal neoplasia; PPP1R46; Protein APC; protein phosphatase 1, regulatory subunit 46; RATAPC; truncated adenomatosis polyposis coli; WNT signaling pathway regulator | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
11789, 24205, 324 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
1.44 mg/mL | |
PBS with 20% glycerol and 0.025% ProClin 300; pH 7 | |
P25054, P70478, Q61315 | |
Apc | |
Synthetic peptide corresponding to a region within amino acids 2767 and 2843 of Human APC. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction