Invitrogen™ PROTEIN S Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA590849

Catalog No. PIPA590849

Description

Immunogen sequence: MDINKPGPLF KPENGLLETK VYFAGFPRKV ESELIKPINP RLDGCIRSWN LMKQGASGIK EIIQEKQNKH CLVTVEKGSY YPGSGIAQFH IDYNNVSSAE GWHVNVTLNI RPSTGTGVML ALVSGNNTVP FAVSLVDSTS EKSQDILLSV ENTVIYRIQA LSLCSDQQSH LEFRVNRNNL ELSTPLKIET ISHEDLQRQL AVLDKAMKAK VATYLGGLPD VPFSATPVNA FYNGCMEVNI NGVQLDLDEA ISKHNDIRAH SCPSVWKKTK NS; Positive Samples: LO2, HeLa, 293T, Mouse liver, Mouse kidney, Rat liver, Rat kidney.

Protein S is a vitamin K-dependent, potent neutral anticoagulant plasma glycoprotein. Protein S has a molecular weight of approximately 70 kDa and consists of a single polypeptide chain. The concentration of protein S in human plasma is 25 μg/mL, with a half-life of approximately two days. About 40% of Protein S in plasma is in a free form, whereas 60% is complexed with C4b-binding Protein (C4BP). Only the free Protein S functions as a cofactor to antigen presenting cells (APC) in the APC-dependent degradation of Factor Va and Factor VIIIa.

Specifications

• Antigen: PROTEIN S
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PROS1
• Gene Alias: AW214361; Preproprotein S; PROS; PROS 1; PROS1; protein S; protein S (alpha); Protein S alpha; protein Sa; proteinS; PS 21; PS 22; PS 23; PS 24; PS 25; PS 26; PS21; PS22; PS23; PS24; PS25; PS26; PSA; rabbit protein S; THPH5; THPH6; unnamed protein product; vitamin K-dependent plasma protein S; vitamin K-dependent protein S; vitamin K-dependent protein S precursor
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19128, 5627, 81750
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.74 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P07225, P53813, Q08761
• Gene Symbols: PROS1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 405-676 of human PROS1 (NP_0003042).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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