Invitrogen™ PRP8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528721

Catalog No. PIPA528721

Description

Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (100%), Xenopus laevis (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.

Specifications

• Antigen: PRP8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Prpf8
• Gene Alias: 220 kDa U5 snRNP-specific protein; apoptosis-regulated protein 1; apoptosis-regulated protein 2; AU019467; D11Bwg0410e; DBF3/PRP8; H PRPC8; HPRP8; id:ibd1257; ik:tdsubc_2a9; im:7141966; p220; precursor mRNA processing protein; pre-mRNA processing factor 8; pre-mRNA-processing-splicing factor 8; Prp8; PRP8 homolog; PRP8 pre-mRNA processing factor 8 homolog; PRPC8; prpf8; RP13; Sfprp8l; SNRNP220; spl; Splicing factor Prp8; tdsubc_2a9; U5 snRNP-specific protein; U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p; wu:fb37c02; wu:fb73e06; xx:tdsubc_2a9; zgc:56504
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10594
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q6P2Q9
• Gene Symbols: Prpf8
• Immunogen: Synthetic peptide corresponding to a region within amino acids 1978 and 2072 of Human PRP8.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov