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Invitrogen™ PRPF18 Polyclonal Antibody
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Catalog No. PIPA5101774
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PIPA5101774 100 μL
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Catalog No. PIPA5101774 Supplier Invitrogen™ Supplier No. PA5101774
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total PRPF18.

PRPF18 (pre-mRNA-splicing factor 18), also known as HPRP18, is a 342 amino acid protein that localizes to nuclear speckles and plays a role in the second step of pre-mRNA splicing. A member of the PRP18 family, PRPF18 contains seven WD repeats and exists as two alternatively spliced isoforms which are encoded by a gene located on human chromosome 10p13. Chromosome 10 contains over 800 genes and 135 million nucleotides. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. Other chromosome 10 associated disorders include Cockayne syndrome, tetrahydrobiopterin deficiency and trisomy 10.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRPF18
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene PRPF18
Gene Accession No. Q8BM39, Q99633, Q9JKB8
Gene Alias 2810441A10Rik; HPRP18; HPRP18 homolog; Kcrf; Potassium channel regulatory factor; Pprf18; pre-mRNA processing factor 18; pre-mRNA-splicing factor 18; Prp18; PRP18 homolog; PRP18 pre-mRNA processing factor 18 homolog; PRP18 pre-mRNA processing factor 18 homolog (yeast); PRP18 pre-mRNA processing factor 18 homolog(PRPF18); Prpf18
Gene Symbols PRPF18
Host Species Rabbit
Immunogen A synthesized peptide derived from human PRPF18(Accession Q99633), corresponding to amino acid residues D181-R231.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171552, 67229, 8559
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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