Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA590145

Invitrogen™ PRPK Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA590145
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA590145 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA590145 Supplier Invitrogen™ Supplier No. PA590145
Only null left
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: MAAARATTPA DGEEPAPEAE ALAAARERSS RFLSGLELVK QGAEARVFRG RFQGRAAVIK HRFPKGYRHP ALEARLGRRR TVQEARALLR CRRAGISAPV VFFVDYASNC LYMEEIEGSV TVRDYIQSTM ETEKTPQGLS NLAKTIGQVL ARMHDEDLIH GDLTTSNMLL KPPLEQLNIV LIDFGLSFIS ALPEDKGVDL YVLEKAFLST HPNTETVFEA FLKSYSTSSK KARPVLKKLD EVRLRGRKRS MVG; Positive Samples: HT-29, BxPC3, 293T, HeLa, Jurkat, Mouse testis, Mouse thymus, Rat testis; Cellular Location: Nucleus.

Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (PubMed:22912744, PubMed:27903914). The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 (PubMed:22912744, PubMed:27903914). TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP. Atypical protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation (PubMed:11546806). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRPK
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.37 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Tp53rk
Gene Accession No. Q96S44
Gene Alias 2810408M09Rik; 4933401B08Rik; 5630401H01Rik; Atypical serine/threonine protein kinase TP53RK; BUD32; C20orf64; dJ101A2; EKC/KEOPS complex subunit TP53RK; mNori-2p; Nori-2; Nori-2p; p53-related protein kinase; PRPK; TP53 regulating kinase; TP53-regulating kinase; TP53RK; transformation related protein 53 regulating kinase; Trp53 regulating kinase; Trp53rk; Trp53tk
Gene Symbols Tp53rk, Trp53rkb
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-253 of human TP53RK (NP_2910283).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 112858, 362272, 76367
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.