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Invitrogen™ PSAP Polyclonal Antibody
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Catalog No. PIPA521340
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100 μL
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PIPA521340 100 μL
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Catalog No. PIPA521340 Supplier Invitrogen™ Supplier No. PA521340
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: U87-MG, SK-N-SH, SK-N-AS, mouse brain, rat brain. Predicted reactivity: Pig (87%), Bovine (86%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

PSAP is a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PSAP
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.98 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Psap
Gene Accession No. P07602, P10960, Q61207
Gene Alias A1 activator; AI037048; Cerebroside sulfate activator; Co-beta-glucosidase; Component C; CSAct; Dispersin; GLBA; Glucosylceramidase activator; Proactivator polypeptide; prosaposin; prosaposin (sulfated glycoprotein, sphingolipid hydrolase activator); Protein A; Protein C; Psap; SAP1; SAP-1; SAP-2; Saposin-A; Saposin-B; Saposin-B-Val; Saposin-C; Saposin-D; Sgp1; SGP-1; SGP1A; snoRNA MBII-198; Sphingolipid activator protein 1; Sphingolipid activator protein 2; sphingolipid activator protein-1; sulfated glycoprotein 1; Sulfatide/GM1 activator
Gene Symbols Psap
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human PSAP. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19156, 25524, 5660
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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