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AdipoGen Pseudouridimycin
SDP

Supplier:  AdipoGen AGCN20316M001

Encompass_Preferred

Chemical. CAS 1566586-52-4. Formula C17H26N8O9. MW 486.4. Isolated from Streptomyces sp. Peptidyl nucleoside antibiotic. Selective nucleoside-analog inhibitor of bacterial RNA polymerase RNAP. Inhibits RNAP through a distinctive binding site on RNAP the NTP addition site and mechanism competition with UTP for occupancy of the NTP addition site than Rifampin. Targets bacterial RNAP in Gram-positive and Gram-negative organisms, including antibiotic-resistant isolates and shows extremely low frequency of resistance selection. Potently inhibits bacterial RNAP in vitro, inhibits bacterial growth in culture, and has shown in vivo efficacy in animal models of infection.

Catalog No. 50-256-2607


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