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PSMA/GCPII Mouse anti-Human, Rat, Clone: 3G4E12, Proteintech
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Catalog No. 501737095 Shop All Proteintech Group Inc Products
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50-173-7095 150 μL
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Catalog No. 50-173-7095 Supplier Proteintech Group Inc Supplier No. 666781IG150UL
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Description

Mouse Monoclonal Antibody

PMSA (FOLH1) is a type II transmembrane glycoprotein belonging to the M28 peptidase family. Three functionally distinct proteins are encoded, including folylpoly-gamma-glutamate carboxypeptidase in the intestine, N-acetylated alpha-linked acidic dipeptidase 1 in the brain, and prostate-specific membrane antigen in the prostate. A mutation in the intestinal form may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. The form expressed in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. The prostate form is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region.

Specifications

Antigen PSMA/GCPII
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 3G4E12
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene FOLH1
Gene Accession No. P70627, Q04609
Gene Alias FGCP, Folate hydrolase 1, FOLH, FOLH1, GCP2, GCPII, Glutamate carboxypeptidase 2, Glutamate carboxypeptidase II, mGCP, NAALAD1, NAALAdase, NAALADase I, PSM, PSMA
Gene Symbols Folh1
Host Species Mouse
Immunogen PSMA/GCPII Fusion Protein Ag16594
Purification Method Protein G
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2346, 85309
Target Species Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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