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Invitrogen™ PSMB7 Polyclonal Antibody
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Catalog No. p-7184314
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100 μL
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PIPA5111352 100 μL
PIPA5111404 100 μL
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Catalog No. PIPA5111352 Supplier Invitrogen™ Supplier No. PA5111352
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LVSEAIAAGI FNDLGSGSNI DLCVISKNKL DFLRPYTVPN KKGTRLGRYR CEKGTTAVLT EKITPLEIEV LEETVQTM Highest antigen sequence indentity to the following orthologs: Rat - 92%, Mouse - 95%.

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit. This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit).
TRUSTED_SUSTAINABILITY

Specifications

Antigen PSMB7
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Psmb7
Gene Accession No. Q99436
Gene Alias AU020723; beta-type proteasome 7 subunit; EGK_07890; hypothetical protein LOC511207; macropain chain Z; MC14; Mmc14; Multicatalytic endopeptidase complex chain Z; proteasome (prosome, macropain) subunit, beta type 7; proteasome (prosome, macropain) subunit, beta type, 7; proteasome 20S subunit beta 7; proteasome beta 7 subunit; proteasome catalytic subunit 2; proteasome subunit alpha; proteasome subunit beta 7; proteasome subunit beta type-7; proteasome subunit beta type-7 proprotein; proteasome subunit Z; protein serine kinase c17; Psmb7; RP11-101K10.7; Z
Gene Symbols Psmb7
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human PSMB7. Recombinant protein control fragment (Product #RP-92975).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5695
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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