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Invitrogen™ PTCH Polyclonal Antibody
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Catalog No. PIPA5142733
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100 μg
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PIPA5142733 100 μg
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Catalog No. PIPA5142733 Supplier Invitrogen™ Supplier No. PA5142733
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Description

Goat Polyclonal Antibody

Additional Information: This antibody is expected to recognize all reported isoforms (NP_000255.2; NP_001077072.1; NP_001077071.1; NP_001077073.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.

This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PTCH
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Ptch1
Gene Accession No. Q13635, Q61115
Gene Alias A230106A15Rik; BCNS; etID309849.2; FLJ26746; FLJ42602; HGNC:9585; HPE7; lep; leprechaun; mes; mesenchymal dysplasia; NBCCS; OTTHUMP00000021709; OTTHUMP00000021710; patched; Patched 1; patched 2; patched homolog 1; patched homolog 2; patched protein; patched1; patched-2 protein; patched-like protein; protein patched homolog 1; Ptc; ptc1; ptc-1; ptc2; Ptch; PTCH protein +12b; PTCH protein +4'; PTCH protein -10; PTCH protein -3; PTCH protein -3,4,5; PTCH1; Ptch1 protein +12b; PTCH11; Ptch2; RP11-435O5.3
Gene Symbols Ptch1
Host Species Goat
Immunogen Peptide with sequence C-EELKKINYQVDSWEE.
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19206, 5727
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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