Invitrogen™ PTH1R Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA3205

Catalog No. PIPA3205

Description

PA3-205 detects PTHR1 in human samples. PA3-205 has successfully been used in Western blot, immunocytochemical, and immunohistochemical (paraffin) procedures. The PA3-205 immunogen is a synthetic peptide corresponding to the C-terminal amino acids E(573)EASGPERPPALLQEEWETVM(593) of PTHR1.

Parathyroid hormone receptor 1 is a member of the G-protein coupled receptor family. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Parathyroid hormone receptor 1 has been reported to be expressed in bone, breast, brain, colon, GI, kidney, liver, placenta, skin, umbilical cord, and uterus.

Specifications

• Antigen: PTH1R
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Pth1r
• Gene Alias: MGC138426; MGC138452; Parathormone; Parathyrin; parathyroid hormone 1 receptor; parathyroid hormone receptor; parathyroid hormone receptor 1; parathyroid hormone/parathyroid hormone-related peptide receptor; parathyroid hormone/parathyroid hormone-related protein receptor; PFE; PPR; PTH; PTH/PTHr receptor; PTH/PTHrP receptor; PTH/PTHrP type I receptor; PTH1 receptor; PTH1R; Pthr; Pthr1; PTHrel; PTH-related peptide receptor; PTHrP-R; PTHrP-receptor; seven transmembrane helix receptor
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: Conc. Not Determined
• Formulation: whole serum with 0.02% sodium azide
• Gene Accession No.: Q03431
• Gene Symbols: Pth1r
• Immunogen: Synthetic peptide corresponding to the C-terminal amino acids E(573)EASGPERPPALLQEEWETVM(593) of PTHR1.
• Regulatory Status: RUO
• Gene ID (Entrez): 5745
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

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