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Invitrogen™ PTMA Polyclonal Antibody
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Catalog No. 01674415
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200 μg
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Catalog No. Quantity
01-674-415 200 μg
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Catalog No. 01-674-415 Supplier Invitrogen™ Supplier No. PA19532
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Description

Chicken Polyclonal Antibody

PA1-9532 detects Thymosin in human, mouse, pig and rat samples. PA1-9532 has been successfully used in ELISA procedures. PA1-9532 immunogen is a synthetic peptide based on human thymosin protein.

The thymus gland produces several hormones or hormone-like substances which are derived from a polypeptide precursor containing (in the rat) 113 amino acids and known as prothymosin-alpha. A peptide containing 28 amino acid residues, named thymosin-alpha-1, was originally isolated from calf thymosin fraction 5 and shown to restore various aspects of immune function in several in vitro and invivo test systems. Thymosin-alpha-1 was subsequently isolated from a similar fraction from human thymosin and reported to have the same amino acid sequence as bovine thymosin-alpha-1. In 2003, Jiang et al. identified a pathway that regulates mitochondria-initiated caspase activity. In this pathway, putative human HLA class II-associated protein (PHAP) promoted caspase-9 activation after apoptosome formation, whereas prothymosin-alpha-1 negatively regulated caspase-9 activation by inhibiting apoptosome formation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PTMA
Applications ELISA
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene PTMA
Gene Accession No. P06302, P06454, P26350
Gene Alias alpha-prothymosin; gene sequence 28; prothymosin alpha; prothymosin alpha protein; Prothymosin alpha, N-terminally processed; prothymosin, alpha; prothymosin-alpha; PTMA; Thym; thymosin; Thymosin alpha; Thymosin alpha-1; TMSA; TMSB4; TMSB4X
Gene Symbols PTMA
Host Species Chicken
Immunogen Synthetic peptide based on human thymosin protein.
Purification Method Affinity chromatography
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100294684, 19231, 29222, 5757
Target Species Human, Mouse, Rat, Pig
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgY
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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