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Invitrogen™ PTP1B Polyclonal Antibody

Rabbit Polyclonal Antibody

$559.50

Specifications

Antigen	PTP1B
Concentration	1 mg/mL
Content And Storage	-20°C, Avoid Freeze/Thaw Cycles, store in dark
Applications	Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification	Polyclonal

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PIPA5109252 View Documents View Product Certificates View Alternatives and Save Up to	Invitrogen™ PA5109252	100 μL	Each for $559.50	Only null left	Sign In or Register to check your price. Add to Cart

Description

Positive Control: Mouse prostate tissue, SiHa, HUVEC, LOVO, human tonsil tissue, human colon cancer tissue, human kidney tissue, human placenta tissue.

PTP1B (PTPN1) is a tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. It mediates dephosphorylation of EIF2AK3/PERK and in turn inactivates the protein kinase activity of EIF2AK3/PERK. PTP1B also plays a role in CKII- and p60c-src-induced signal transduction cascades. It regulates the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. PTP1B also regulates the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.

Specifications

Antigen	PTP1B
Content And Storage	-20°C, Avoid Freeze/Thaw Cycles, store in dark
Classification	Polyclonal
Form	Liquid
Isotype	IgG
Target Species	Human
Gene	PTPN1
Gene Alias	CPTP1; EC 3.1.3.48; EGK_02300; hgnc9642; KIAA0283; protein tyrosine phosphatase 1B; protein tyrosine phosphatase non-receptor type 1; protein tyrosine phosphatase, non-receptor type 1; protein tyrosine phosphatase, placental; protein-protein-tyrosine phosphatase HA2; protein-tyrosine phosphatase 1B; Protein-tyrosine phosphatase HA2; PTN1; Ptp; PTP1B; PTP-1B; ptp1b protein; PTP-HA2; Ptpn1; RP5-1121H13.2; RPTPrho; tyrosine phosphatase 1b; tyrosine-phosphatase; Tyrosine-protein phosphatase non-receptor type 1; wu:fk54h03
Gene Symbols	PTPN1
Primary or Secondary	Primary
Purification Method	Affinity Chromatography

Concentration	1 mg/mL
Applications	Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Conjugate	Unconjugated
Host Species	Rabbit
Regulatory Status	RUO
Formulation	PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.	P18031
Gene ID (Entrez)	5770
Immunogen	Recombinant protein within Human PTP1B aa 1-191.
Product Type	Antibody

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Invitrogen™ PTP1B Polyclonal Antibody

Specifications

Description

Specifications

Documents