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Invitrogen™ PTPN23 Polyclonal Antibody
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Catalog No. PIPA592262
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100 μL
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PIPA592262 100 μL
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Catalog No. PIPA592262 Supplier Invitrogen™ Supplier No. PA592262
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DSNRVVLRSG KDDYINASCV EGLSPYCPPL VATQAPLPGT AADFWLMVHE QKVSVIVMLV SEAEMEKQKV ARYFPTERGQ PMVHGALSLA LSSVRSTETH VERVLSLQFR DQSLKRSLVH LHFPTWPELG LPDSPSNLLR FIQEVHAHYL HQRPLHTPII VHCSSGVGRT GAFALLYAAV QEVEAGNGIP ELPQLVRRMR QQRKHMLQEK LHLRFCYEAV V; Positive Samples: Mouse eye, Rat kidney; Cellular Location: Cytoplasm, Cytoplasmic vesicle, Early endosome, Endosome, Nucleus, cilium basal body, cytoskeleton.

Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PTPN23
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.51 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PTPN23
Gene Accession No. O88902, Q6PB44
Gene Alias AI462446; HDPTP; HD-PTP; His domain-containing protein tyrosine phosphatase; Kiaa1471; Protein tyrosine phosphatase TD14; protein tyrosine phosphatase, non-receptor type 23; PTPN23; PTP-TD14; Tyrosine-protein phosphatase non-receptor type 23
Gene Symbols PTPN23
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1230-1450 of human PTPN23 (NP_0562811).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 104831, 117552
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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