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  6. Invitrogen™ PTPRB Monoclonal Antibody (122.2)

Invitrogen™ PTPRB Monoclonal Antibody (122.2)

Catalog No. 01674947 Shop All Thermo Scientific Products
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Catalog No. Quantity
01-674-947 50 μL
01-674-948 100 μL
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Catalog No. 01-674-947 Supplier Invitrogen™ Supplier No. MA15869
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Description

Mouse Monoclonal Antibody

Predicted molecular weight: 224 kDa.

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation. Alternate transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PTPRB
Applications Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 122.2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene PTPRB
Gene Accession No. 0
Gene Alias 3230402H02Rik; C130094E24; HPTPB; HPTP-BETA; protein tyrosine phosphatase, receptor type B; protein tyrosine phosphatase, receptor type, B; protein tyrosine phosphatase, receptor type, beta polypeptide; protein-tyrosine phosphatase beta; PTPB; Ptprb; Ptpz; receptor-type tyrosine-protein phosphatase beta; Rptpb; R-PTP-BETA; vascular endothelial protein tyrosine phosphatase; VEPTP; VE-PTP
Gene Symbols PTPRB
Host Species Mouse
Immunogen Embryonic rat brain proteoglycans.
Purification Method Size-exclusion - Dialysis
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 314843
Target Species Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgM
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