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Invitrogen™ PTPRM Polyclonal Antibody
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Catalog No. PIPA533009
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50 μg
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PIPA533009 50 μg
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Catalog No. PIPA533009 Supplier Invitrogen™ Supplier No. PA533009
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Bovine, Dog, Elephant, Panda, Rabbit, Opossum (100%); Mouse, Rat, Bat, Horse (94%); Hamster, Chicken (88%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PTPRM
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene PTPRM
Gene Accession No. P28827
Gene Alias hR-PTPu; Kiaa4044; MGC166994; mKIAA4044; protein tyrosine phosphatase mu; protein tyrosine phosphatase receptor type M; protein tyrosine phosphatase receptor-type M; protein tyrosine phosphatase, receptor type M; protein tyrosine phosphatase, receptor type, M; protein tyrosine phosphatase, receptor type, mu polypeptide; protein tyrosine phosphatase, receptor-type, M; protein-tyrosine phosphatase mu; PTP mu; Ptpmu; PTPRL1; PTPRM; receptor-type tyrosine-protein phosphatase mu; RPTPM; RPTPmu; R-PTP-MU; RPTPU
Gene Symbols PTPRM
Host Species Rabbit
Immunogen Synthetic 16 amino acid peptide from internal region of human PTPRM.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100356969, 480203, 536092, 5797
Target Species Human, Canine, Rabbit, Monkey, Bovine
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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