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Invitrogen™ PTX3 Polyclonal Antibody
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Catalog No. PIPA598102
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100 μg
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PIPA598102 100 μg
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Catalog No. PIPA598102 Supplier Invitrogen™ Supplier No. PA598102
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Description

Rabbit Polyclonal Antibody

PTX3 Polyclonal Antibody for ELISA, ICC/IF, IHC (P), Western Blot

Pentraxins are a protein superfamily that is characterized by a cyclic multimeric structure. Ptx3, also known as tumor necrosis factor-stimulated gene sequence-14 (TSG14), is a secreted pattern-recognition receptor that has a non-redundant role in resistance to selected microbial agents. Ptx3 belongs to the family of 'long pentraxins', which have C-terminal pentraxin domains and novel amino-terminal domains. Ptx3 binds selected pathogens, including Aspergillus fumigatus, Pseudomonas aeruginosa and Salmonella typhimurium. It is synthesized in IgA glomerulonephritis and activates mesangial cells. Secretion of Ptx3 in adipose cells can be induced by TNF. Ptx3 is also involved in amplification of inflammatory reactions and regulation of innate immunity. The human PTX3 gene maps to chromosome 3q25.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PTX3
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene PTX3
Gene Accession No. P26022
Gene Alias AI607804; long pentraxin 3; pentaxin related; pentaxin-related protein PTX3; pentraxin 3; pentraxin 3, long; pentraxin related; pentraxin related gene; pentraxin-related protein PTX3; Ptx3; TNF alpha-induced protein 5; TNFAIP5; Tsg14; TSG-14; Tumor necrosis factor alpha-induced protein 5; tumor necrosis factor-inducible gene 14 protein; tumor necrosis factor-inducible protein TSG-14
Gene Symbols PTX3
Host Species Rabbit
Immunogen Recombinant Human Pentraxin-related protein PTX3 protein (99-164AA).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5806, 689388
Target Species Human, Rat
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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