PXN Monoclonal Antibody (OTI1H10), TrueMAB™, OriGene

Catalog No.	Quantity
50-168-3937	100 μL

Catalog No. 50-168-3937 Supplier OriGene Supplier No. TA811256

Description

Mouse Monoclonal Antibody

Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.

Specifications

• Antigen: PXN
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI1H10
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: PXN
• Gene Accession No.: P49023, Q8VI36
• Gene Alias: paxillin
• Gene Symbols: Pxn
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human PXN produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 19303, 5829
• Target Species: Human, Mouse
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1