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Tocris Bioscience™ PYR 41

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10mg
Description
Cell-permeable, irreversible ubiquitin-activating enzyme (E1) inhibitor (IC50 < 10 μM). Blocks ubiquitination and prevents ubiquitin-mediated proteasomal degradation. Inhibits NF-κB activation, blocks degradation of p53, increases p21 levels and induces apoptosis in vitro. Also causes an increase in sumoylation of proteins.
Specifications
Specifications
CAS | 418805-02-4 |
Quantity | 10 mg |
Molecular Formula | C17H13N3O7 |
Formula Weight | 371.3 |
Purity | >98% |
Molecular Weight (g/mol) | 371.305 |
Chemical Name or Material | PYR 41 |
Safety and Handling
Recommended Storage | Store at -20°C |
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