Pyridine-2,3-dicarboxylic acid, 99%

Description

CAS: 89-00-9 | C7H5NO4 | 167.12 g/mol

Quinolinic acid is an endogenous NMDA agonist. Quinolinic acid is a metabolite of tryptophan that acts as a putative NMDA receptor agonist. Quinolinic acid is an excitotoxic metabolite and an agonist of N-methyl-D-aspartate receptors. properties of KYNA raise the possibility of a functional link between KYNA and QUIN in the brain which may be of relevance for an understanding of human neurodegenerative disorders. Quinolinic acid is a potent endogenous excitant at amino acid receptors in CNS.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Quinolinic acid is an endogenous NMDA agonist. Quinolinic acid is a metabolite of tryptophan that acts as a putative NMDA receptor agonist. Quinolinic acid is an “excitotoxic” metabolite and an agonist of N-methyl-D-aspartate receptors. properties of KYNA raise the possibility of a functional link between KYNA and QUIN in the brain which may be of relevance for an understanding of human neurodegenerative disorders. Quinolinic acid is a potent endogenous excitant at amino acid receptors in CNS.

Solubility
Soluble in water (partly), alkalies, dilute aqueous base, DMSO, and alcohol (slightly).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 89-00-9
• Molecular Formula: C7H5NO4
• Molecular Weight (g/mol): 167.12
• MDL Number: MFCD00006295
• InChI Key: GJAWHXHKYYXBSV-UHFFFAOYSA-N
• Synonym: quinolinic acid, 2,3-pyridinedicarboxylic acid, quinolinate, pyridine-2,3-dicarboxylate, unii-f6f0hk1urn, 2,3-pyridinedicarboxylicacid, pyridine-2,3-carboxylate, f6f0hk1urn, pyridin-2,3-dicarbonsaeure, 2,3-pyridinedicarboxylate
• PubChem CID: 1066
• ChEBI: CHEBI:16675
• IUPAC Name: pyridine-2,3-dicarboxylic acid
• SMILES: C1=CC(=C(N=C1)C(=O)O)C(=O)O

• Melting Point: ∼188°C (decomposition)
• Quantity: 100 g
• Beilstein: 137110
• Merck Index: 14,8073
• Solubility Information: Soluble in water (partly),alkalies,dilute aqueous base,DMSO,and alcohol (slightly).
• Formula Weight: 167.12
• Percent Purity: 99%
• Chemical Name or Material: Pyridine-2,3-dicarboxylic acid

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	201-874-8
RTECSNumber	US7967250
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only