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Invitrogen™ Pyruvate Carboxylase Polyclonal Antibody
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Catalog No. PIPA518874
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100 μg
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PIPA518874 100 μg
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Catalog No. PIPA518874 Supplier Invitrogen™ Supplier No. PA518874
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Goat Polyclonal Antibody

This antibody is predicted to react with bovine, canine, human, porcine and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.

Pyruvate Carboxylase requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Pyruvate Carboxylase
Applications Flow Cytometry, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene PC
Gene Accession No. P11498
Gene Alias EC 6.4.1.1; Pc; Pcb; Pcx; PYC; pyruvate carboxylase; pyruvate carboxylase, mitochondrial; pyruvate decarboxylase; pyruvic carboxylase
Gene Symbols PC
Host Species Goat
Immunogen Synthetic peptide sequence (KFKEVKKAYVEANQ) corresponding to the internal amino acids of PC (aa 886-900).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5091
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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