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Invitrogen™ PYY Polyclonal Antibody
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Catalog No. PIPA5110763
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100 μL
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PIPA5110763 100 μL
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Catalog No. PIPA5110763 Supplier Invitrogen™ Supplier No. PA5110763
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PIKPEAPGED ASPEELNRYY ASLRHYLNLV TRQRYGKRDG PDRLLSKTFF PDGEDRPVRS RSEGPDLW Highest antigen sequence indentity to the following orthologs: Mouse - 73%, Rat - 74%.

Peptide tyrosine-tyrosine amide (3-36), or PYY (3-36), is a major metabolite of the gut hormone PYY and is produced by the action of dipeptidyl peptidase IV on PYY in the intestinal brush border and in the circulation. PYY (3-36) is a potent inhibitor of food intake in rats and humans, acting selectively on the Y2 receptor to inhibit orexigenic NPY neurons in the arcuate nucleus, thus disinhibiting anorexigenic POMC neurons. The anorexigenic effect of PYY (3-36) is additive to that of the co-secreted gut hormone GLP-1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PYY
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Pyy
Gene Accession No. P10082
Gene Alias GHYY; Peptide tyrosine tyrosine; peptide tyrosine-tyrosine (YY); peptide YY; peptide YY (mapped); Peptide YY(3-36); Peptide YY3-36; Peptide YY3-37; peptide-YY; prepro-PYY; PYY; PYY II; PYY1; PYY-1; PYY-2; PYYI; PYY-I; PYYII; PYY-II; RATGHYY; Yy
Gene Symbols Pyy
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human PYY. Recombinant protein control fragment (Product #RP-90212).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5697
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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