Qa-2 Mouse, anti-Mouse, R718, Clone: 1-1-2, BD OptiBuild™

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 751930

Catalog No. BDB751930

Description

The 1-1-2 monoclonal antibody specifically recognizes the Qa-2 MHC class Ib antigen, which is expressed at higher levels on mature T lymphocytes than on B cells. Its expression is upregulated in the late stages of T-cell maturation. Qa-2 is a 40 kDa GPI-linked cell surface molecule encoded by the Q5, Q6, Q7, and/or Q9 genes of the H-2 complex. A 39 kDa soluble form results from alternative splicing of the transcript. Although Qa-2 is nonpolymorphic, its level of expression on both T and B lymphocytes varies among inbred mouse strains. High expressors include strains carrying the H-2[b] haplotype low expressors include H-2[d] strains, and H-2[k] strains are Qa-2-negative.

Specifications

• Antigen: Qa-2
• Clone: 1-1-2
• Format: Liquid
• Quantity: 50 μg
• Storage Requirements: Refrigerate Upon Arrival
• Monoclonal or Polyclonal: Monoclonal

• Applications: Flow Cytometry
• Conjugate: R718
• Host Species: Mouse
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Mouse