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Qa-2 Mouse, anti-Mouse, R718, Clone: 1-1-2, BD OptiBuild™
Mouse Monoclonal Antibody
Supplier: BD Biosciences 751930
Description
The 1-1-2 monoclonal antibody specifically recognizes the Qa-2 MHC class Ib antigen, which is expressed at higher levels on mature T lymphocytes than on B cells. Its expression is upregulated in the late stages of T-cell maturation. Qa-2 is a 40 kDa GPI-linked cell surface molecule encoded by the Q5, Q6, Q7, and/or Q9 genes of the H-2 complex. A 39 kDa soluble form results from alternative splicing of the transcript. Although Qa-2 is nonpolymorphic, its level of expression on both T and B lymphocytes varies among inbred mouse strains. High expressors include strains carrying the H-2[b] haplotype low expressors include H-2[d] strains, and H-2[k] strains are Qa-2-negative.

Specifications
Qa-2 | |
Monoclonal | |
R718 | |
50 μg | |
Primary | |
Refrigerate Upon Arrival |
Flow Cytometry | |
1-1-2 | |
Mouse | |
RUO | |
Mouse | |
Liquid |
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