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Qa-2 Mouse, anti-Mouse, R718, Clone: 1-1-2, BD OptiBuild™

Catalog No. BDB751930 Shop All BD Biosciences Products
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BDB751930 50 μg
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Catalog No. BDB751930 Supplier BD Biosciences Supplier No. 751930
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Description

Mouse Monoclonal Antibody

The 1-1-2 monoclonal antibody specifically recognizes the Qa-2 MHC class Ib antigen, which is expressed at higher levels on mature T lymphocytes than on B cells. Its expression is upregulated in the late stages of T-cell maturation. Qa-2 is a 40 kDa GPI-linked cell surface molecule encoded by the Q5, Q6, Q7, and/or Q9 genes of the H-2 complex. A 39 kDa soluble form results from alternative splicing of the transcript. Although Qa-2 is nonpolymorphic, its level of expression on both T and B lymphocytes varies among inbred mouse strains. High expressors include strains carrying the H-2[b] haplotype low expressors include H-2[d] strains, and H-2[k] strains are Qa-2-negative.

TRUSTED_SUSTAINABILITY

Specifications

Antigen Qa-2
Applications Flow Cytometry
Classification Monoclonal
Clone 1-1-2
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Refrigerate Upon Arrival
Form Liquid
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