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Invitrogen™ QKI Recombinant Rabbit Monoclonal Antibody (JE55-71)
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Catalog No. PIMA542512
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100 μL
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PIMA542512 100 μL
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Catalog No. PIMA542512 Supplier Invitrogen™ Supplier No. MA542512
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Control: K562 cell lysate, Hela cell lysate, A549, mouse brain tissue. Subcellular Location: Nucleus, Cytoplasm.

This gene encodes the sacsin protein, which includes a UbL domain at the N-terminus, a DnaJ domain, and a HEPN domain at the C-terminus. The gene is highly expressed in the central nervous system, also found in skin, skeletal muscles and at low levels in the pancreas. This gene includes a very large exon spanning more than 12.8 kb. Mutations in this gene result in autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS), a neurodegenerative disorder characterized by early-onset cerebellar ataxia with spasticity and peripheral neuropathy. Sacsin has been found to protect against mutant ataxin-1. A pseudogene associated with this gene is located on chromosome 11. Alternative splicing of this gene results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen QKI
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone JE55-71
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene QKI
Gene Accession No. Q96PU8, Q9QYS9
Gene Alias 1110003F05Rik; 1500005P18; DKFZp586I0923; HKQ; homolog of mouse quaking QKI (KH domain RNA binding protein); Hqk; hqkI; l(17)-1Wis; l17Wis1; lethal, Chr 17, U Wisconsin 1; MqkI; Protein quaking; protein quaking-like; Qk; QK1; QK3; Qka1; Qki; QKI, KH domain containing RNA binding; QKI, KH domain containing, RNA binding; QKI-5 protein; quaking; quaking homolog, KH domain RNA binding; RNA Binding (QKI); RNA binding protein HQK; rqkI
Gene Symbols Qk, QKI
Host Species Rabbit
Immunogen Synthetic peptide within C-terminal Human QKI.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19317, 9444
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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