R&D Systems™ Quantikine Immunoassay Control 1137 for Human Serum TIM-1

Catalog No. QC229

Supplier: R&D Systems™ QC229

Description

Immunoassay control set for Human T Cell Immunoglobulin Mucin-1 protein

TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types, epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, glycoproteins of number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate phagocytosis, clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation, enhances Th2 cytokine production. TIM-1 serves as cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus. Polymorphisms are associated with susceptibility to atopy, autoimmunity, severe hepatitis A virus infection in humans. A soluble form of TIM-1 is elevated in urine during nephropathy.

• Storage: Store unopened product at 2 to 8°C. Do not use past expiration date.

Specifications

• Content And Storage: Store the unopened product at 2°C to 8°C. Do not use past expiration date.
• Type: Control Set for ELISA Kit
• Gene ID (Entrez): 26762 (Human); 171283 (Mouse); 286934 (Rat); 102141332 (Cynomolgus Monkey)
• Intended Use: For quantitative measurement of T cell immunoglobulin protein levels
• Product Name: Immunoassay Control Set 920
• Source: Human
• Target Gene: T Cell Immunoglobulin Mucin-1

For Research Use Only