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(R)-(+)-3-Hydroxypyrrolidine, 99%, ee 99%
Description
(R)-(+)-3-Hydroxypyrrolidine is used in the enantioselective addition of diethylzinc to aromatic aldehydes leading to optically active secondary alcohols. Also used to prepare-κ-opioid receptor agonists.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
(R)-(+)-3-Hydroxypyrrolidine is used in the enantioselective addition of diethylzinc to aromatic aldehydes leading to optically active secondary alcohols. Also used to prepare-κ-opioid receptor agonists.
Solubility
Soluble in water and methanol.
Notes
Store under inert gas. It is sensitive to moisture. Store in a cool, dry conditions in well sealed containers. It is hygroscopic and sensitive to air. Incompatible with oxidizing agents.

Specifications
Specifications
Melting Point | 15°C |
Density | 1.048 |
Boiling Point | 108°C to 110°C (8 mmHg) |
Flash Point | >110°C (230°F) |
Refractive Index | 1.49 |
Quantity | 5 g |
Beilstein | 5376132 |
Sensitivity | Air sensitive; Hygroscopic |
Solubility Information | Soluble in water and methanol. |
Optical Rotation | +6.5° (c=3.5 in Methanol) |
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Safety and Handling
Hazard Category | H315-H319-H335 |
Hazard Statement | GHS H Statement H315-H319 Causes skin irritation. Causes serious eye irritation. |
Precautionary Statement | P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c |
TSCA | No |
Recommended Storage | Ambient temperatures |
RUO – Research Use Only
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