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  7. (R)-(+)-3-Hydroxypyrrolidine, 99%, ee 99%

(R)-(+)-3-Hydroxypyrrolidine, 99%, ee 99%

Catalog No. AAL1949906
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Catalog No. AAL1949906 Supplier Thermo Scientific Chemicals Supplier No. L1949906
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Description

CAS: 2799-21-5 | C4H9NO | 87.122 g/mol

(R)-(+)-3-Hydroxypyrrolidine is used in the enantioselective addition of diethylzinc to aromatic aldehydes leading to optically active secondary alcohols. Also used to prepare-κ-opioid receptor agonists.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
(R)-(+)-3-Hydroxypyrrolidine is used in the enantioselective addition of diethylzinc to aromatic aldehydes leading to optically active secondary alcohols. Also used to prepare-κ-opioid receptor agonists.

Solubility
Soluble in water and methanol.

Notes
Store under inert gas. It is sensitive to moisture. Store in a cool, dry conditions in well sealed containers. It is hygroscopic and sensitive to air. Incompatible with oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 2799-21-5
Molecular Formula C4H9NO
Molecular Weight (g/mol) 87.122
MDL Number MFCD00145220
InChI Key JHHZLHWJQPUNKB-SCSAIBSYSA-N
Synonym r-3-hydroxypyrrolidine, r-pyrrolidin-3-ol, r-3-pyrrolidinol, 3r-pyrrolidin-3-ol, 3r-3-pyrrolidinol, r-hydroxypyrrolidine, r-+-3-hydroxypyrrolidine, r-hp, 3-pyrrolidinol, 3r, 3r-pyrrolidinol
PubChem CID 2759337
IUPAC Name (3R)-pyrrolidin-3-ol
SMILES C1CNCC1O

Specifications

Melting Point 15°C
Density 1.048
Boiling Point 108°C to 110°C (8 mmHg)
Flash Point >110°C (230°F)
Refractive Index 1.49
Quantity 5 g
Beilstein 5376132
Sensitivity Air sensitive; Hygroscopic
Solubility Information Soluble in water and methanol.
Optical Rotation +6.5° (c=3.5 in Methanol)
Formula Weight 87.12
Percent Purity 99%
Assay ee 99%
Chemical Name or Material (R)-(+)-3-Hydroxypyrrolidine
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Safety and Handling

Hazard Category H315-H319-H335
Hazard Statement GHS H Statement
H315-H319
Causes skin irritation.
Causes serious eye irritation.
Precautionary Statement P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA No
Recommended Storage Ambient temperatures
SDS

RUO – Research Use Only

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