Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ ABT 089 Dihydrochloride
  6. 507950R

Tocris Bioscience™ ABT 089 Dihydrochloride

High affinity and selective α4β2 nAChR partial agonist

Supplier:  Tocris Bioscience™ 5079/50

 View more versions of this product

Catalog No. 507950R


Add to Cart
This item is not returnable. View return policy

Description

Description

ABT 089 dihydrochloride is a high affinity and selective α4β2 partial agonist (Ki = 16 nM). Exhibits >1000-fold and >10,000-fold selectivity for α4β2 over α1β1γ1 and α7 receptors respectively. Neuroprotective against glutamate-induced toxicity in rat cortical neurons in vitro. Enhances cognitive performance in vivo. Orally bioavailable and brain penetrant.
Specifications

Specifications

ABT 089 dihydrochloride
2-Methyl-3-[(2S)-pyrrolidinylmethoxy]pyridine dihydrochloride
Soluble to 100mM in water and to 20mM in DMSO
265.18
Bioactive Small Molecule
161416-61-1
50 mg
C11H16N2O·2HCl
Solid
>98%
Product Suggestions

Product Suggestions

Safety and Handling

Safety and Handling

Recommended Storage : Desiccate at Room Temperature

SDS
Documents

Documents

Product Certifications
Promotions

Promotions

Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit

Research Use Only. Not For Human or Veterinary Use