R&D Systems ABT 089 Dihydrochloride, Tocris™

High affinity and selective α4β2 partial agonist

Manufacturer: R&D Systems 5079/50

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Catalog No. 507950R

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Research Use Only. Not For Human or Veterinary Use


    Physical Form Solid,Solid
    Chemical Name or Material ABT 089 dihydrochloride
    Product Type Bioactive Small Molecules
    CAS 161416-61-1
    Assay Percent Range >98%
    Molecular Formula C11H16N2O·2HCl
    Formula Weight 265.18
    Synonym 2-Methyl-3-[(2S)-pyrrolidinylmethoxy]pyridine dihydrochloride
    Recommended Storage Desiccate at room temperature.
    Quantity 50mg
    Solubility Soluble to 100mM in water and to 20mM in DMSO

    • Exhibits >1000-fold and >10,000-fold selectivity for α4β2 over α1β1γ1 and α7 receptors respectively
    • Neuroprotective against glutamate-induced toxicity in rat cortical neurons in vitro
    • Enhances cognitive performance in vivo
    • Orally bioavailable and brain penetrant

  • Description & Specifications

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