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R&D Systems™ Caspase-3 Inhibitor Z-DEVD-FMK

Catalog No. FMK004
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FMK004 1 mg
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Description

Used as cell-permeable, irreversible inhibitor of caspase activity. R&D Systems Caspase-3 Inhibitor Z-DEVD-FMK binds to the active site of activated proteases irreversibly and inhibits apoptosis.

  • Fluoromethyl ketone (FMK)-derivatized peptides are useful tools for studying caspase activity
  • Used in tissue cultures to inhibit apoptosis at final working concentrations of 50nM to 100μM
  • Regulated by a variety of stimili, including APAF1, CFLAR/FLIP, NOL3/ARC, IAP, BIRC1/NAIP, BIRC2/cIAP-1, BIRC3/cIAP-2, BIRC4/XIAP, BIRC5/Survivin and BIRC7/Livin

Specifications

Content And Storage Store the unopened product at -20 to -70° C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Quantity 1 mg
Product Type Caspase-3
Molecular Weight (g/mol) 668Da
Inhibitors Z-DEVD-FMK
Form Lyophilized

For research use only. Not for use in diagnostic procedures

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