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R&D Systems™ Recombinant Human MSP/MST1 (CHO-expressed) Protein, CF

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Manufacturer:  R&D Systems™ 352MCH010

Catalog No. 352MCH010

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Measured by its ability to activate MSP R/Ron in MDA-MB-453 or T47D human breast cancer cells. 80 ng/mL of the recombinant human MSP significantly induces phosphorylation of MSP R/Ron measured by the Human Phospho-MSP R/Ron DuoSet™ IC Kit (Catalog # DYC1947 ). Measured by its binding ability in a functional ELISA. When Recombinant Human MSPR/Ron Protein (Catalog # 1947-MS) is represent at 100 ng/mL (100 μg/mL), The concentration of Recombinant Human MSP/MST1 that produces 50% optimal binding response is found to be 8-40 ng/mL.


10 µg
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
<0.10 EU / 1 µg of the protein by the LAL method.
Reconstitute at 100 µg/mL in sterile PBS.
Lyophilized from a 0.2 µm filtered solution in PBS.
M.W. (Observed): 85 kDa, non-reducing conditions; M.W. (theoretical): 53 kDa (alpha-chain), 25 kDa (beta-chain)
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Chinese Hamster Ovary cell line, CHO-derived human MSP/MST1 protein Gln19-Arg483 (alpha-chain) & Val484-Gly711 (beta-chain)
Disulfide-linked heterodimer
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